MISPhyl: Mutual Information Supermatrix Phylogenomics pipeline


Tok, Pendy and Tan, Joon Liang (2022) MISPhyl: Mutual Information Supermatrix Phylogenomics pipeline. In: 2022 10th International Conference on Information and Communication Technology (ICoICT), 2-3 August 2022, Bandung, Indonesia.

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Classification of species, particularly pathogens are important in understanding mode of infections, their origins and even treatments. The advancement of sequencing technologies has offered a parallel advancement in species classification with the used of phylogenomics. The success of phylogenomics requires a series of bioinformatics methods and procedures, which would be a challenge for most clinical analysts or researchers. Herein, we present MISPhyl (Mutual Information Supermatrix Phylogenomics), an automated pipeline developed to facilitate the reconstruction of high confidence supermatrix tree using the median-ranked single-copy core orthologous genes (SCGs) evaluated via mutual information in annotated genome sets. In house accessory scripts for sequence quality assessments, renaming FASTA headers and subsampling based on mutual information are distributed along with MISPhyl, made publicly available (https://github.com/pendy05/MISPhyl).

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: Mutual information, phylogenomics, genomics
Subjects: Q Science > QA Mathematics > QA71-90 Instruments and machines
Divisions: Faculty of Information Science and Technology (FIST)
Depositing User: Ms Nurul Iqtiani Ahmad
Date Deposited: 30 Nov 2022 04:38
Last Modified: 30 Nov 2022 04:38
URII: http://shdl.mmu.edu.my/id/eprint/10761


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