Citation

Ahmad Kayani, Aminuddin and Marzuki, Marini and Khoo, Alan Soo Beng and Chan, Jun Yuan (2019) Exposure of MDA-MB-231 Cells to Dielectrophoretic Fields for Electroporation and Cancer Diagnostics. In: 2018 IEEE-EMBS Conference on Biomedical Engineering and Sciences (IECBES), 3-6 Dec. 2018, Sarawak, Malaysia.

Text 78.pdf - Published Version Restricted to Repository staff only Download (1MB)

Abstract

This paper presents the experimental analysis of exposing breast cancer cells (MDA-MB-231) to dielectrophoretic (DEP) fields on a curved microelectrode platform. The platform was composed of arrays of curved microelectrodes which were patterned onto a glass slide and samples containing MDA-MB-231 cells were pipetted onto the surface of the platform. The MDA-MB-231 cells were suspended in DMEM media to assess the cells behaviour and effects when exposed to DEP fields in different concentrations of DMEM media. Finite element method was utilised to characterise the electric field gradient and DEP field and numerical simulations were used to determine DEP response of the cells. We performed experimental work to observe DEP effects and confirmed the DEP responses obtained from the simulations.

Item Type:	Conference or Workshop Item (Paper)
Uncontrolled Keywords:	Dielectrophoresis
Subjects:	Q Science > QC Physics > QC501-766 Electricity and magnetism
Divisions:	Faculty of Engineering and Technology (FET)
Depositing User:	Ms Suzilawati Abu Samah
Date Deposited:	11 Jan 2022 04:19
Last Modified:	11 Jan 2022 04:19
URII:	http://shdl.mmu.edu.my/id/eprint/8966

Downloads

Edit (login required)