Citation

Alborno, Ayat Jamal and Hassan, Hasliza and Khan, Nasreen and Dorasamy, Magiswary (2026) Bio-entrepreneurial Intention in Bio-Innovation Service Ecosystems: A Systematic Review of Key Determinants. Journal of Logistics, Informatics and Service Science, 13 (2). pp. 177-197. ISSN 2409-2665

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Abstract

Bio-entrepreneurial intention plays a critical role in enabling bio-innovation and sustainable value creation within science-driven service ecosystems. While prior studies have identified various psychological, educational, institutional, and policy-related determinants of Bio-entrepreneurial intention, this body of research remains conceptually fragmented and largely focused on isolated factors. This systematic literature review aims to consolidate and critically interpret recent empirical evidence on the determinants of Bio-entrepreneurial intention, with particular attention to how individual cognition interacts with bio-innovation service structures and innovation-support mechanisms. Following PRISMA 2020 guidelines, a structured literature search was conducted in the Scopus database covering studies published between 2020 and 2024. From an initial pool of 5,673 records, seven peer-reviewed empirical studies met the inclusion criteria. Data were analyzed using qualitative thematic synthesis to identify recurring psychological, educational, institutional, and ecosystem-related determinants shaping Bio-entrepreneurial intention. The synthesis identified seven key determinants: bio-innovation ecosystem support, Bio-entrepreneurial education, university spin-off mechanisms, government and policy support, environmental and regulatory conditions, entrepreneurial self-efficacy, and entrepreneurial attitude. Rather than operating as independent predictors, these determinants are interpreted as interconnected enabling conditions within bio-innovation service systems. The synthesis indicates that educational services, ecosystem support, and institutional arrangements shape perceived feasibility, legitimacy, and motivation by facilitating knowledge flows, innovation logistics, and technology transfer pathways. Entrepreneurial self-efficacy and attitude mediate how these systemic inputs are internalized at the individual level. Given the limited and emerging evidence base, the findings should be interpreted as exploratory and agenda-setting rather than generalizable. The contribution of this review lies not in proposing a new conceptual framework, but in clarifying Bio-entrepreneurial intention as a system-embedded phenomenon arising from the interaction between individual cognition and innovation support services. The study offers implications for bio-innovation education, policy design, and service-oriented ecosystem development, and outlines directions for future research toward more integrative and theory-driven models of Bio-entrepreneurial intention.

Item Type:	Article
Uncontrolled Keywords:	Bio-entrepreneurship, Systematic Review, PRISMA, Biotechnology Innovation, Entrepreneur Intention, Sustainable entrepreneurship
Subjects:	H Social Sciences > HB Economic theory. Demography > HB522-715 Income. Factor shares > HB615-715 Entrepreneurship. Risk and uncertainty. Property
Divisions:	Faculty of Management (FOM)
Depositing User:	Ms Suzilawati Abu Samah
Date Deposited:	02 Mar 2026 00:09
Last Modified:	02 Mar 2026 00:15
URII:	http://shdl.mmu.edu.my/id/eprint/15374

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