Citation

Chan, Jun Yuan and Chan, Yee Kit and Lim, Heng Siong (2021) Extremely Low Frequency Electromagnetic Field (ELF-EMF) Exposure Studies on Cancer and Normal Cells for Bioelectromagnetic Cancer Applications. In: 2nd FET PG Engineering Colloquium Proceedings 2021, 1-15 Dec. 2021, Online Conference. (Unpublished)

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Abstract

"1) In depth review of existing ELF-EMF cancer literature. i. Review existing literature of current progress of research. ii. Summarise findings reported by studies by systematic tabulation, comparison and categorization. iii. Summarise potential developments for future research that can 2) ELF-EMF simulation of experimental setup and model cell samples. i. Conduct ELF-EMF simulations of model in-vitro setup with model cell lines ii. Propose to incorporate biothermodynamic principals into ELF-EMF exposure model Biochemical Thermodynamic Principle (BTP): the heat wasted by the cell is evaluated by considering the usual equation of heat exchange between a solid (soft matter) system and the fluid around it. Frequency of Resonance: represents the natural frequency of a cell necessary to maintain the non- equilibrium steady state. A schematic diagram depicting the changes in conversion of energy of target cells when exposed to specific ELF-EMF frequencies. The model describes the changes of metabolism and growth of cancer cells that a cancer cell experiences when specific ELF-EMF frequencies are applied. Under normal conditions, cells are in equilibrium between the dormant and proliferating conditions as energy from nutrients (E) is transformed into work (W). Exposure of cells to resonance ELF-EMF frequencies changes the dynamics of energy conversion in the cells where demand for energy in the form of ATP for maintaining ion flux balance increases at the expense of proliferation. 3) ELF-EMF exposure cellular activity studies with biochemical tests in lab. i. Proposed cellular activity biochemical studies: cell proliferation/viability, mitochondrial activity. ii. Propose to expand cellular activity biochemical studies with ELF-EMF exposure parameters to further characterize cellular responses. (HSP 70 studies) Experimental Setup: Helmholtz Coil (Dual Circle coil spaced one radius apart for homogneous EMF exposure region in the middle between the coils.), In vitro Cell samples: 96 well plate, CO2 incubator"

Item Type:	Conference or Workshop Item (Paper)
Uncontrolled Keywords:	Electromagnetic field, bioelectromagnetism, cancer
Subjects:	Q Science > QC Physics > QC501-766 Electricity and magnetism
Divisions:	Faculty of Engineering and Technology (FET)
Depositing User:	Ms Nurul Iqtiani Ahmad
Date Deposited:	28 Jan 2022 01:50
Last Modified:	28 Jan 2022 01:50
URII:	http://shdl.mmu.edu.my/id/eprint/9888

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