Dielectrophoresis-based microfluidic platforms for cancer diagnostics


Chan, Jun Yuan and Ahmad Kayani, Aminuddin and Md Ali, Mohd Anuar and Kok, Chee Kuang and Majlis, Burhanuddin Yeop and Hoe, Susan Ling Ling and Marzuki, Marini and Khoo, Alan Soo Beng and Ostrikov, Kostya (Ken) and Rahman, Md. Ataur and Sriram, Sharath (2018) Dielectrophoresis-based microfluidic platforms for cancer diagnostics. Biomicrofluidics, 12 (1). 011503. ISSN 1932-1058

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The recent advancement of dielectrophoresis (DEP)-enabled microfluidic platforms is opening new opportunities for potential use in cancer disease diagnostics. DEP is advantageous because of its specificity, low cost, small sample volume requirement, and tuneable property for microfluidic platforms. These intrinsic advantages have made it especially suitable for developing microfluidic cancer diagnostic platforms. This review focuses on a comprehensive analysis of the recent developments of DEP enabled microfluidic platforms sorted according to the target cancer cell. Each study is critically analyzed, and the features of each platform, the performance, added functionality for clinical use, and the types of samples, used are discussed. We address the novelty of the techniques, strategies, and design configuration used in improving on existing technologies or previous studies. A summary of comparing the developmental extent of each study is made, and we conclude with a treatment of future trends and a brief summary.

Item Type: Article
Uncontrolled Keywords: Dielectrophoresis
Subjects: Q Science > QC Physics > QC501-766 Electricity and magnetism > QC501-(721) Electricity
Divisions: Faculty of Engineering and Technology (FET)
Depositing User: Ms Rosnani Abd Wahab
Date Deposited: 25 Oct 2020 21:35
Last Modified: 25 Oct 2020 21:35
URII: http://shdl.mmu.edu.my/id/eprint/7248


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