Mamba-Based VoxelMorph Framework for Cardiovascular Disease Imaging and Risk Assessment

Citation

Jabbar, Muhammad Kashif and Jianjun, Huang and Jabbar, Ayesha and Ur Rehman, Zaka (2025) Mamba-Based VoxelMorph Framework for Cardiovascular Disease Imaging and Risk Assessment. IEEE Access, 13. pp. 78120-78137. ISSN 2169-3536

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Abstract

Cardiovascular diseases (CVDs), particularly coronary artery disease (CAD), remain the leading cause of global mortality, necessitating advanced diagnostic solutions. Accurate deformable image registration plays a crucial role in enhancing segmentation precision and classification performance in cardiovascular imaging. However, existing registration methods, including VoxelMorph, face limitations in computational efficiency and memory usage, restricting their real-time applicability for high-resolution cardiac imaging. This study proposes the Mamba-Optimized VoxelMorph framework, which leverages GPU-based parallelization and memory optimization to address these challenges. The framework achieves superior registration accuracy, yielding a Dice Similarity Coefficient (DSC) of 0.95 and Normalized CrossCorrelation (NCC) of 0.90, while reducing computational time by 40% and memory usage to 800 MB. These advancements ensure efficient alignment of complex cardiac structures, thereby improving segmentation accuracy and classification reliability. By addressing these critical limitations, the Mamba-Optimized VoxelMorph framework significantly enhances cardiovascular imaging, enabling precise, scalable, and real-time deformable image registration for improved CAD diagnosis and treatment planning.

Item Type: Article
Uncontrolled Keywords: Cardiovascular disease (CVD), imaging component analysis
Subjects: R Medicine > RA Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine
Divisions: Faculty of Engineering (FOE)
Depositing User: Ms Rosnani Abd Wahab
Date Deposited: 30 May 2025 02:11
Last Modified: 30 May 2025 02:11
URII: http://shdl.mmu.edu.my/id/eprint/13887

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