Citation

Shee Da En, Zuriel and Mhd Noor, Ervina Efzan and Ahmed Kayani, Aminuddin and Hussin, Mohd Hazwan and Baig, Mirza Farrukh (2024) Electrochemical Impedance Spectroscopy in the Determination of the Dielectric Properties of Tau-441 Protein for Dielectrophoresis Response Prediction. Bioengineering, 11 (7). p. 698. ISSN 2306-5354

Text Electrochemical Impedance Spectroscopy in the Determination of the Dielectric Properties of Tau-441 Protein for Dielectrophoresis Response Prediction.pdf - Published Version Restricted to Repository staff only Download (2MB)

Abstract

This study employs electrochemical impedance spectroscopy (EIS) to probe the behavior of Tau-441 protein, a key component implicated in Alzheimer’s disease. Through meticulous experimentation and analysis, the impedance of Tau-441 protein suspension revealed a conductivity peak value of 1.02 S/m. The study demonstrates a high level of specificity and selectivity, particularly within the challenging nanomolar concentration range. Additionally, the EIS method enabled the prediction of Tau-441 protein’s dielectrophoresis (DEP) response and the determination of the associated frequency range of 1 kHz to 1 MHz. These findings contribute to advancing our understanding of the molecular intricacies surrounding Tau-441 and hold promise for unraveling implications related to Alzheimer’s disease. This study establishes a robust foundation for future research on neurodegenerative disease and biosciences, offering valuable insights into the electrochemical dynamics of Tau-441 protein

Item Type:	Article
Uncontrolled Keywords:	dielectrophoresis
Subjects:	Q Science > QC Physics > QC501-766 Electricity and magnetism > QC501-(721) Electricity
Divisions:	Faculty of Engineering and Technology (FET)
Depositing User:	Ms Nurul Iqtiani Ahmad
Date Deposited:	02 Sep 2024 07:48
Last Modified:	02 Sep 2024 07:48
URII:	http://shdl.mmu.edu.my/id/eprint/12917

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